HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → 3-Methoxy-4-nitrophenol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | 3-Fluoro-4-nitrophenol | HCID 520948 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Solvent | HCID 178502595 | HCID 178502595 | — |
| Product | 3-Methoxy-4-nitrophenol | HCID 12900532 | — |
Reaction Steps
To a solution of 3-Fluoro-4-nitro-phenol (15.7 g, 100 mmol) in THF (300 mL), 30% KOMe in Methanol (49 mL, 210 mmol) is added at 0° C. The mixture is heated to gentle reflux for 18 hours.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07964592B2 |
| Source dataset | uspto-grants-2011_06 |
| ORD ID | ord-0d3c1dc25e7e4dae9a9ed20d093dd933 |
| Source note | uspto-grants-2011_06 |