HCID 86625259, compound → HCID 178461558, compound

Participants

Reaction Conditions

Reaction Steps

D8 (2.20 g, 5.63 mmol) was taken up in 25% TFA in DCM (50 ml) and stirred for 4 h at 25° C. The solvent was removed in vacuo and the residue dissolved in DCM (50 ml), washed with saturated NaHCO3, dried (Na2SO4) and concentrated to yield the title compound as an orange foam (1.64 g). δH (CDCl3) 1.43 (6H, d), 2.48 (2H, dd), 2.97 (2H, d), 3.88 (2H, s), 4.15-4.75 (2H, br d), 6.40 (1H, d), 7.64 (1H, d), 8.93 (1H, br s). MS (ES): MH+ 291.

Provenance & Evidence