HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,4-Bis(trifluoromethyl)benzoyl chloride → HCID 11477830, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,4-Bis(trifluoromethyl)benzoyl chloride | HCID 2736126 | — |
| Reactant | N-(2-cyclopropylethyl)-6-(1-piperazinyl)-3-pyridazinecarboxamide | HCID 66849327 | — |
| Product | HCID 11477830 | HCID 11477830 | — |
Reaction Steps
Following the procedure of Example 3, making variations only as required to use 2,4-bis-trifluoromethylbenzoyl chloride in place of isoxazole-5-carbonyl chloride to react with 6-piperazin-1-yl-pyridazine-3-carboxylic acid (2-cyclopropylethyl)amide, the title compound was obtained as a white powder (29% yield). 1H NMR (400 MHz, CDCl3) δ 8.08, 8.02-7.98, 7.91, 7.54, 7.03, 3.97-3.86, 3.85-3.72, 3.57, 3.36, 1.52, 0.77-0.74, 0.49-0.46, 0.12-0.09.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07964591B2 |
| Source dataset | uspto-grants-2011_06 |
| ORD ID | ord-6f2767267052466c990752067a925752 |
| Source note | uspto-grants-2011_06 |