HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-[2-(Trifluoromethyl)benzoyl]piperazine → HCID 16035661, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-[2-(Trifluoromethyl)benzoyl]piperazine | HCID 16733784 | — |
| Reactant | 6-Chloro-N-[2-(4-methoxyphenyl)ethyl]-3-pyridazinecarboxamide | HCID 60859189 | — |
| Product | HCID 16035661 | HCID 16035661 | — |
Reaction Steps
Following the procedure of Example 15, making variations only as required to use 6-chloropyridazine-3-carboxylic acid [2-(4-methoxyphenyl)ethyl]amide in place of 6-chloropyridazine-3-carboxylic acid (2-cyclopropyl-2-hydroxyethyl)amide to react with piperazin-1-yl-(2-trifluoromethylphenyl)methanone, the title compound was obtained as a white solid (12% yield). 1H NMR (400 MHz, CDCl3) δ 8.04, 7.93, 7.74, 7.63, 7.56, 7.36, 7.12, 6.92, 6.81, 4.08-3.46, 3.33, 2.87.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07964591B2 |
| Source dataset | uspto-grants-2011_06 |
| ORD ID | ord-11d22f9505d94b059db0e2c2335b9c3d |
| Source note | uspto-grants-2011_06 |