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HRID242474

反应详情

EQUATION

反应方程式

HRID 242474 的结构方程式

REACTANTS

反应物

5
结构：O=C(Cl)c1cc(F)c(F)cc1F
HCID145164

2,4,5-Trifluorobenzoyl chloride

C7H2ClF3O

结构：CC(C)(C)OC(=O)N1CCC(=O)CC1
HCID735900

1-Boc-4-piperidone

C10H17NO3

结构：O=C(Cl)c1ccc(F)c(F)c1
HCID2724519

3,4-Difluorobenzoyl chloride

C7H3ClF2O

结构：CC(C)(C)OC(=O)N1CCCCC(=O)C1
HCID22831870

tert-Butyl 3-oxoazepane-1-carboxylate

C11H19NO3

结构：CNC(=O)[C@@H](NC(=O)n1nc(-c2cc(F)c(F)cc2F)c2c1CCN(C)C2)C(C)(C)C
HCID46863441

未命名化合物

PRODUCTS

生成物

1
结构：CNC(=O)[C@@H](NC(=O)n1nc(-c2ccc(F)c(F)c2)c2c1CCCCN2C)C(C)(C)C
HCID59345359

未命名化合物

PROCEDURE

实验过程

Compound 69 was prepared according to the procedure described above for the synthesis of compound 37 except that 1-Boc-4-piperidone was replaced with tert-butyl 3-oxoazepane-1-carboxylate and 2,4,5-trifluorobenzoyl-chloride was replaced with 3,4-difluorobenzoylchloride. LCMS (+ESI) m/z=434.2 [M+H]+.