5-amino-1-(2-methoxyphenyl)-1H-pyrazole-4-carboxamide → HCID 15428980, compound

HRID 2424766Notes

Reaction equation

HRID 2424766 reaction equation
[NH2:1][C:2]1[N:6]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9]C=2OC)[N:5]=[CH:4][C:3]=1[C:15]([NH2:17])=[O:16].N[C:19]1N(C2CCCC2)N=C(C)C=1C#N>>[NH2:1][C:2]1[N:6]([CH:7]2[CH2:12][CH2:11][CH2:10][CH2:9]2)[N:5]=[C:4]([CH3:19])[C:3]=1[C:15]([NH2:17])=[O:16]

Participants

3

Reactant 2

HCID 121517035-amino-1-(2-methoxyphenyl)-1H-pyrazole-4-carboxamideHCID 15428981HCID 15428981, compound

Product 1

HCID 15428980HCID 15428980, compound

Procedure

Following the procedure for the preparation of 5-amino-1-(2-methoxyphenyl)-1H-pyrazole-4-carboxamide but substituting 5-amino-1-cyclopentyl-3-methyl-1H-pyrazole-4-carbonitrile provided the title compound. 1H NMR (300 MHz, CDCl3): δ 5.39 (br, 2H), 5.32 (br, 2H), 4.26 (m, 1H), 2.38 (s, 3H), 2.04 (m, 4H), 1.9 (m, 2H), 1.66 (m, 2H).

Sources & evidence

ORD record
ord-e79fbc170a924f45ba9b13e6019a2d50
Source dataset
uspto-grants-2011_06
Patent number
US07964607B2

Reaction notes

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