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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 242477Generated: October 25, 2026

beta-Alaninamide → (S)-N-(1-(3-amino-3-oxopropylamino)-3,3-dimethyl-1-oxobutan-2-yl)-5-methyl-3-(2,4,5-trifluorophenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine-1-carboxamide

https://huagongshe.com/reaction/242477

Reaction equation

Participants

RoleNameHCIDCharge
Reactantbeta-AlaninamideHCID 192802—
ReactantN-((S)-1-((S)-1-amino-4-methyl-1-oxopentan-2-ylamino)-3,3-dimethyl-1-oxobutan-2-yl)-5-methyl-3-(2,4,5-trifluorophenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine-1-carboxamideHCID 46861923—
Product(S)-N-(1-(3-amino-3-oxopropylamino)-3,3-dimethyl-1-oxobutan-2-yl)-5-methyl-3-(2,4,5-trifluorophenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine-1-carboxamideHCID 46861924—

Reaction Steps

Compound 73 was prepared according to the procedure described for the synthesis of compound 72 by replacing leucine amide with 3-aminopropanamide. LCMS (+ESI) m/z=495.4 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08653127B2
Source datasetuspto-grants-2014_02
ORD IDord-ffc49bd9bd9b49a5a5b5829d85ea1b93
Source noteuspto-grants-2014_02