HRID2424782

反应详情

EQUATION

反应方程式

REACTANTS

反应物

反应SMILES：CC[C@@H]1CN(Cc2ccccc2)C[C@H]1c1nc2c(cnn2C(C)C)c(=O)[nH]1

HCID135875910

未命名化合物

反应SMILES：C[C@@H]1CNC[C@H]1c1nc2c(cnn2C2CCCC2)c(=O)[nH]1

HCID136128455

未命名化合物

PRODUCTS

产物

反应SMILES：CC[C@@H]1CNC[C@H]1c1nc2c(cnn2C(C)C)c(=O)[nH]1

HCID136128514

未命名化合物

PROCEDURE

实验过程

Following the procedure for the preparation of 1-cyclopentyl-6-[(3S,4S)-4-methylpyrrolidin-3-yl]-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one but substituting 6-[(3S,4S)-1-benzyl-4-ethylpyrrolidin-3-yl]-1-isopropyl-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one provided the title compound. 400 MHz 1H NMR (CD3OD) δ 8.02 (s, 1H), 5.10 (m, 1H), 3.78-3.60 (m, 3H), 3.32-3.28 (m, 1H), 3.10 (m, 1H), 2.62 (m, 1H), 1.65 (m, 1H), 1.58 (m, 1H), 1.49 (dd, J=6.6, 1.7 Hz, 6H), 0.97 (t, J=7.5 Hz, 3H). MS: (M+H m/z=276.1).