HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-amino-1-(2-methoxyphenyl)-1H-pyrazole-4-carbonitrile → 5-Amino-1-(4,4-difluorocyclohexyl)-1h-pyrazole-4-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-amino-1-(2-methoxyphenyl)-1H-pyrazole-4-carbonitrile | HCID 12150560 | — |
| Reactant | (4,4-Difluorocyclohexyl)hydrazine | HCID 55279041 | — |
| Product | 5-Amino-1-(4,4-difluorocyclohexyl)-1h-pyrazole-4-carbonitrile | HCID 58416683 | — |
Reaction Steps
Following the procedure for the preparation of 5-amino-1-(2-methoxyphenyl)-1H-pyrazole-4-carbonitrile but substituting 1-(4,4-difluorocyclohexyl)hydrazine provided the title compound. 400 MHz 1H NMR (CDCl3) δ 7.5 (m, 1H), 3.90 (m, 1H), 2.40-1.00 (m, 8H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07964607B2 |
| Source dataset | uspto-grants-2011_06 |
| ORD ID | ord-d46b4b39ca9c4d09a0195c3ffb219a66 |
| Source note | uspto-grants-2011_06 |