HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,2,2-Trifluoroethylhydrazine → 5-Amino-1-(2,2,2-trifluoroethyl)-1H-pyrazole-4-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,2,2-Trifluoroethylhydrazine | HCID 78740 | — |
| Reactant | 5-amino-1-(2-methoxyphenyl)-1H-pyrazole-4-carbonitrile | HCID 12150560 | — |
| Product | 5-Amino-1-(2,2,2-trifluoroethyl)-1H-pyrazole-4-carbonitrile | HCID 53418333 | — |
Reaction Steps
Following the procedure for the preparation of 5-amino-1-(2-methoxyphenyl)-1H-pyrazole-4-carbonitrile but substituting 1-(2,2,2-trifluoroethyl)hydrazine provided the title compound. 400 MHz 1H NMR (CDCl3) δ 7.60 (s, 1H), 4.59 (m, 2H), 4.40 (brs, 2H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07964607B2 |
| Source dataset | uspto-grants-2011_06 |
| ORD ID | ord-dc4990f665254fc7bff489a3e58334c6 |
| Source note | uspto-grants-2011_06 |