Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Prolinamide, D- → N-((S)-1-((R)-2-carbamoylpyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)-5-methyl-3-(2,4,5-trifluorophenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine-1-carboxamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Prolinamide, D- | HCID 447554 | — |
| 반응물 | N-((S)-1-((S)-1-amino-4-methyl-1-oxopentan-2-ylamino)-3,3-dimethyl-1-oxobutan-2-yl)-5-methyl-3-(2,4,5-trifluorophenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine-1-carboxamide | HCID 46861923 | — |
| 생성물 | N-((S)-1-((R)-2-carbamoylpyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)-5-methyl-3-(2,4,5-trifluorophenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine-1-carboxamide | HCID 46862032 | — |
반응 단계
Compound 75 was prepared according to the procedure described for the synthesis of compound 72 by replacing leucine amide with (R)-pyrrolidine-2-carboxamide. LCMS (+ESI) m/z=521.5 [M+H]+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08653127B2 |
| 출처 데이터셋 | uspto-grants-2014_02 |
| ORD ID | ord-7d7447fb9f424129bfa853885b43bca8 |
| 출처 메모 | uspto-grants-2014_02 |