HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-amino-1-(2-methoxyphenyl)-1H-pyrazole-4-carbonitrile → 5-amino-1-cyclobutyl-1H-pyrazole-4-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-amino-1-(2-methoxyphenyl)-1H-pyrazole-4-carbonitrile | HCID 12150560 | — |
| Reactant | Cyclobutylhydrazine | HCID 18699355 | — |
| Product | 5-amino-1-cyclobutyl-1H-pyrazole-4-carbonitrile | HCID 49853544 | — |
Reaction Steps
Following the procedure for the preparation of 5-amino-1-(2-methoxyphenyl)-1H-pyrazole-4-carbonitrile but substituting 1-cyclobutylhydrazine provided the title compound. 400 MHz 1H NMR (CDCl3) δ 7.50 (s, 1H), 4.48-4.40 (m, 1H), 4.23 (m, 2H), 2.70-2.58 (m, 2H), 2.48-2.35 (m, 2H), 1.97-1.79 (m, 2H). MS: (M+H m/z 163.1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07964607B2 |
| Source dataset | uspto-grants-2011_06 |
| ORD ID | ord-7959455f01b2429481a07961677de492 |
| Source note | uspto-grants-2011_06 |