HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2S)-N-methylpyrrolidine-2-carboxamide → N-((S)-3,3-dimethyl-1-((S)-2-(methyl-carbamoyl)pyrrolidin-1-yl)-1-oxobutan-2-yl)-5-methyl-3-(2,4,5-trifluorophenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine-1-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2S)-N-methylpyrrolidine-2-carboxamide | HCID 10374482 | — |
| Reactant | N-((S)-1-((S)-1-amino-4-methyl-1-oxopentan-2-ylamino)-3,3-dimethyl-1-oxobutan-2-yl)-5-methyl-3-(2,4,5-trifluorophenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine-1-carboxamide | HCID 46861923 | — |
| Product | N-((S)-3,3-dimethyl-1-((S)-2-(methyl-carbamoyl)pyrrolidin-1-yl)-1-oxobutan-2-yl)-5-methyl-3-(2,4,5-trifluorophenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine-1-carboxamide | HCID 59345313 | — |
Reaction Steps
Compound 76 was prepared according to the procedure for the synthesis of compound 72 by replacing leucine amide with (S)-N-methylpyrrolidine-2-carboxamide. LCMS (+ESI) m/z=535.2 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08653127B2 |
| Source dataset | uspto-grants-2014_02 |
| ORD ID | ord-af9b1221eb3e44b1903056759152e5ae |
| Source note | uspto-grants-2014_02 |