HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-amino-1-(2-methoxyphenyl)-1H-pyrazole-4-carbonitrile → 5-amino-1-(tetrahydro-2H-thiopyran-4-yl)-1H-pyrazole-4-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-amino-1-(2-methoxyphenyl)-1H-pyrazole-4-carbonitrile | HCID 12150560 | — |
| Reactant | (Thian-4-yl)hydrazine | HCID 22593899 | — |
| Product | 5-amino-1-(tetrahydro-2H-thiopyran-4-yl)-1H-pyrazole-4-carbonitrile | HCID 58216748 | — |
Reaction Steps
Following the procedure for the preparation of 5-amino-1-(2-methoxyphenyl)-1H-pyrazole-4-carbonitrile but substituting 1-(tetrahydro-2H-thiopyran-4-yl)hydrazine provided the title compound. 400 MHz 1H NMR (CDCl3) δ 7.44 (s, 1H), 4.71 (s, 2H), 3.84-3.76 (m, 1H), 2.80-2.63 (m, 4H), 2.24-2.10 (m, 4H). MS: (M+H m/z 209.1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07964607B2 |
| Source dataset | uspto-grants-2011_06 |
| ORD ID | ord-f171de6cd73c4dbd82b46124de26c8c5 |
| Source note | uspto-grants-2011_06 |