6-Chloromethyl-2-methylpyridinium chloride → 2-[4-(3-Chloro-phenylethynyl)-2-methyl-imidazol-1-ylmethyl]-6-methyl-pyridine

HRID 2424867Notes

Reaction equation

HRID 2424867 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([C:8]#[C:9][C:10]2[N:11]=[C:12]([CH3:15])[NH:13][CH:14]=2)[CH:5]=[CH:6][CH:7]=1.Cl.Cl[CH2:18][C:19]1[CH:24]=[CH:23][CH:22]=[C:21]([CH3:25])[N:20]=1>>[Cl:1][C:2]1[CH:3]=[C:4]([C:8]#[C:9][C:10]2[N:11]=[C:12]([CH3:15])[N:13]([CH2:18][C:19]3[CH:24]=[CH:23][CH:22]=[C:21]([CH3:25])[N:20]=3)[CH:14]=2)[CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 765456-Chloromethyl-2-methylpyridinium chlorideHCID 178432693HCID 178432693, compound

Product 1

HCID 113362252-[4-(3-Chloro-phenylethynyl)-2-methyl-imidazol-1-ylmethyl]-6-methyl-pyridine

Procedure

The title compound, MS: m/e=322.4 (M+H+), was prepared in accordance with the general method of example 1 from 4-(3-chloro-phenylethynyl)-2-methyl-1H-imidazole and 2-chloromethyl-6-methyl-pyridine hydrochloride.

Sources & evidence

ORD record
ord-f34fd7994c1641b0bbd0fe97052a71e0
Source dataset
uspto-grants-2011_06
Patent number
US07964620B2

Reaction notes

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