5-(chloromethyl)-2-methylpyridine hydrochloride → HCID 25159529, compound

HRID 2424876Notes

Reaction equation

HRID 2424876 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([C:8]#[C:9][C:10]2[N:11]=[C:12]([CH3:15])[NH:13][CH:14]=2)[CH:5]=[CH:6][CH:7]=1.Cl.Cl[CH2:18][C:19]1[CH:20]=[CH:21][C:22]([CH3:25])=[N:23][CH:24]=1>>[Cl:1][C:2]1[CH:3]=[C:4]([C:8]#[C:9][C:10]2[N:11]=[C:12]([CH3:15])[N:13]([CH2:18][C:19]3[CH:20]=[CH:21][C:22]([CH3:25])=[N:23][CH:24]=3)[CH:14]=2)[CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 122143395-(chloromethyl)-2-methylpyridine hydrochlorideHCID 178432693HCID 178432693, compound

Product 1

HCID 25159529HCID 25159529, compound

Procedure

The title compound, MS: m/e=322.5 (M+H+), was prepared in accordance with the general method of example 1 from 4-(3-chloro-phenylethynyl)-2-methyl-1H-imidazole and 5-chloromethyl-2-methyl-pyridine hydrochloride.

Sources & evidence

ORD record
ord-1fab8203668f4f548614ddac34c6ab58
Source dataset
uspto-grants-2011_06
Patent number
US07964620B2

Reaction notes

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