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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2424888Generated: October 25, 2026

2-Chloro-5-(chloromethyl)pyridine → 4-[1-(2-Chloro-pyridin-5-ylmethyl)-2-methyl-1H-imidazol-4-ylethynyl]-2-chloro-pyridine

https://huagongshe.com/reaction/2424888

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-5-(chloromethyl)pyridineHCID 155479—
ReactantHCID 178418879HCID 178418879—
Product4-[1-(2-Chloro-pyridin-5-ylmethyl)-2-methyl-1H-imidazol-4-ylethynyl]-2-chloro-pyridineHCID 11210072—

Reaction Steps

The title compound, MS: m/e=343.1 (M+H+), was prepared in accordance with the general method of example 1 from 2-chloro-4-(2-methyl-1H-imidazol-4-ylethynyl)-pyridine and 2-chloro-5-chloromethyl-pyridine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07964620B2
Source datasetuspto-grants-2011_06
ORD IDord-6b49b5ae11a34fb9bfec7a89bf1799cf
Source noteuspto-grants-2011_06