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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2424893Generated: November 1, 2026

Thionyl Chloride → 3-Chloro-5-(chloromethyl)pyridine hydrochloride

https://huagongshe.com/reaction/2424893

Reaction equation

Participants

RoleNameHCIDCharge
ReactantThionyl ChlorideHCID 24386—
Reactant(5-Chloropyridin-3-yl)methanolHCID 25067264—
Product3-Chloro-5-(chloromethyl)pyridine hydrochlorideHCID 67246305—

Reaction Steps

The title compound was prepared in accordance with the general method of example E from 5-(hydroxymethyl)-3-chloropyridine and thionylchloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07964620B2
Source datasetuspto-grants-2011_06
ORD IDord-921d50e0343f45ca8a8a9aaabeb8d959
Source noteuspto-grants-2011_06