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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2424928Generated: October 26, 2026

1,3-Dibromopropane → Ethyl 1-pyridin-3-ylcyclobutane-1-carboxylate

https://huagongshe.com/reaction/2424928

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,3-DibromopropaneHCID 8001—
ReactantEthyl 3-pyridylacetateHCID 96490—
ProductEthyl 1-pyridin-3-ylcyclobutane-1-carboxylateHCID 67246748—

Reaction Steps

Prepared in a similar manner to that described above by reacting ethyl 2-pyridin-3-ylacetate with 1,3-dibromopropane to give ethyl 1-pyridin-3-ylcyclobutane-1-carboxylate which was then hydrogenated to give the desired compound as a brown oil (quantitative reaction).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07964618B2
Source datasetuspto-grants-2011_06
ORD IDord-f374677e9bf0408cab463ad44f34a638
Source noteuspto-grants-2011_06