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HRID242500

反应详情

EQUATION

反应方程式

HRID 242500 的结构方程式

REACTANTS

反应物

2
结构：Cc1cc(N)n[nH]1
HCID93146

1H-Pyrazol-3-amine, 5-methyl-

C4H7N3

结构：CC(C)(C)[C@H](NC(=O)n1nc(-c2ccc(F)c(F)c2)c2c1CCOC2)C(=O)NCCC#N
HCID46862252

未命名化合物

PRODUCTS

生成物

1
结构：Cc1cc(NC(=O)[C@@H](NC(=O)n2nc(-c3ccc(F)c(F)c3)c3c2CCOC3)C(C)(C)C)n[nH]1
HCID46862251

未命名化合物

PROCEDURE

实验过程

Compound 105 was prepared by the procedure described for the synthesis of compound 104 by replacing 2-cyanoethylamine with 3-amino-5-methylpyrazole. LCMS (+ESI) m/z=473.3 [M+H]+. 1H NMR (CDCl3) δ 8.15 (d, J=9.8 Hz, 1H), 7.50-7.56 (m, 1H), 7.28-7.30 (m, 1H), 7.22-7.27 (m, 1H), 5.84 (d, J=9.9 Hz, 1H), 5.48 (s, 2H), 4.82 (s, 2H), 3.93 (t, J=5.6 Hz, 2H), 3.18 (t, J=4.8 Hz, 2H), 2.17 (s, 3H), 1.11 (s, 9H).