HRID242501

反应详情

EQUATION

反应方程式

HRID 242501 的结构方程式

PROCEDURE

实验过程

Compound 106 was prepared by the procedure described for the synthesis of compound 104 by replacing 2-cyanoethylamine with 2-aminomethyl-5-methylpyrazine. LCMS (+ESI) m/z=499.3 [M+H]+. 1H NMR (CDCl3) δ 8.48 (s, 1H), 8.35 (s, 1H), 7.92 (d, J=9.4 Hz, 1H), 7.47-7.52 (m, 1H), 7.28-7.32 (m, 1H), 7.19-7.27 (m, 1H), 6.98 (br, 1H), 4.82 (s, 2H), 4.57-4.62 (m, 2H), 4.30 (d, J=10.4 Hz, 1H), 3.93 (t, J=5.4 Hz, 2H), 3.18 (br, 2H), 2.80 (s, 3H), 1.11 (s, 9H).