HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chlorophenol → Ethyl 2-(2-chlorophenoxy)acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chlorophenol | HCID 7245 | — |
| Reactant | Ethyl bromoacetate | HCID 7748 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | Ethyl 2-(2-chlorophenoxy)acetate | HCID 302826 | — |
Reaction Steps
The title compound was prepared by reacting 2-chloro-phenol, with ethyl 2-bromoacetate and K2CO3 in DMF. Yield, 97%, colourless oil; 1H NMR (CDCl3): 1.29 (3H, t, J=6.3, CH2CH3), 4.29 (2H, q, J=6.3, CH2CH3), 4.72 (2H, s, OCH2), 6.76 (1H, d, J=8.2, H-6), 6.95 (1H, m, H-4), 720 (1H, m, H-5), 7.40 (1H, dd, J=8.2, H-3).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07964628B2 |
| Source dataset | uspto-grants-2011_06 |
| ORD ID | ord-05587367395c47739e8519fe862b49e0 |
| Source note | uspto-grants-2011_06 |