1,4-Bis(bromomethyl)-2-fluorobenzene → HCID 59154331, compound
Reaction equation
BrCC1C=CC(CBr)=CC=1[F:11].[NH2:12][CH2:13][C:14]1[CH:21]=[CH:20][C:17]([CH2:18][NH2:19])=[CH:16][C:15]=1Cl>>[NH2:12][CH2:13][C:14]1[CH:21]=[CH:20][C:17]([CH2:18][NH2:19])=[CH:16][C:15]=1[F:11]Participants
3
Procedure
The starting material 4-aminomethyl-3-fluoro-benzylamine was prepared from 1,4-bis-bromomethyl-2-fluoro-benzene as described for 4-aminomethyl-3-chloro-benzylamine in example 59a
Sources & evidence
- ORD record
- ord-9c7ea4bfd7ae4801b2f45a63e41d8ca5
- Source dataset
- uspto-grants-2011_06
- Patent number
- US07964633B2
Reaction notes
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