HuagongsheHuagongshe Chemistry Print Report · For research reference only
Toluene → 4'-Bromo-biphenyl sulfonyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Toluene | HCID 1140 | — |
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 4'-Bromo-biphenyl sulfonic acid | HCID 86620295 | — |
| Product | 4'-Bromo-biphenyl sulfonyl chloride | HCID 12371533 | — |
Reaction Steps
4′-Bromo-biphenyl sulfonic acid (5 g) was refluxed in thionyl chloride (30 mL) with a catalytic quantity of DMF (0.5 mL) for 4 hours. Toluene was added and the solvents evaporated under vacuum. The residue collected was recrystallised from petrol/ethyl acetate to give the title compound as large colourless crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07964643B2 |
| Source dataset | uspto-grants-2011_06 |
| ORD ID | ord-ec6aa64d501540b68935c6cd13268384 |
| Source note | uspto-grants-2011_06 |