4-Amino-1-butanol → 4-Bromo-2-fluoro-N-(4-hydroxybutyl)benzene-1-sulfonamide

HRID 2425154Notes

Reaction equation

HRID 2425154 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([S:8](Cl)(=[O:10])=[O:9])=[C:4]([F:12])[CH:3]=1.[NH2:13][CH2:14][CH2:15][CH2:16][CH2:17][OH:18]>>[OH:18][CH2:17][CH2:16][CH2:15][CH2:14][NH:13][S:8]([C:5]1[CH:6]=[CH:7][C:2]([Br:1])=[CH:3][C:4]=1[F:12])(=[O:10])=[O:9]

Participants

3

Reactant 2

HCID 258684-Amino-1-butanolHCID 27363104-Bromo-2-fluorobenzene-1-sulfonyl chloride

Product 1

HCID 160947274-Bromo-2-fluoro-N-(4-hydroxybutyl)benzene-1-sulfonamide

Procedure

Using a method analogous to that described in Example 1, 4-bromo-2-fluorophenyl sulphonyl chloride was reacted with 4-aminobutanol, and the title compound obtained as a white solid after recrystallisation from ether/petrol.

Sources & evidence

ORD record
ord-b407391950f849cc893d732068400bd8
Source dataset
uspto-grants-2011_06
Patent number
US07964643B2

Reaction notes

Loading…