4-Amino-1-butanol → 4-Bromo-N-(4-hydroxybutyl)-3-methylbenzene-1-sulfonamide

HRID 2425156Notes

Reaction equation

HRID 2425156 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([S:8](Cl)(=[O:10])=[O:9])=[CH:4][C:3]=1[CH3:12].[NH2:13][CH2:14][CH2:15][CH2:16][CH2:17][OH:18]>>[OH:18][CH2:17][CH2:16][CH2:15][CH2:14][NH:13][S:8]([C:5]1[CH:6]=[CH:7][C:2]([Br:1])=[C:3]([CH3:12])[CH:4]=1)(=[O:10])=[O:9]

Participants

3

Reactant 2

HCID 258684-Amino-1-butanolHCID 27375034-Bromo-3-methylbenzene-1-sulfonyl chloride

Product 1

HCID 160947244-Bromo-N-(4-hydroxybutyl)-3-methylbenzene-1-sulfonamide

Procedure

Using a method analogous to that described in Example 1, 4-bromo-3-methylphenyl sulphonyl chloride was reacted with 4-aminobutanol, and the title compound obtained as a white solid after recrystallisation from ether/petrol.

Sources & evidence

ORD record
ord-72c23f01bc2545db8b02878aead723fb
Source dataset
uspto-grants-2011_06
Patent number
US07964643B2

Reaction notes

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