4-Ethoxyphenylboronic acid → HCID 11552300, compound

HRID 2425160Notes

Reaction equation

HRID 2425160 reaction equation
[OH:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][NH:7][S:8]([C:11]1[CH:16]=[CH:15][C:14](Br)=[CH:13][CH:12]=1)(=[O:10])=[O:9].[CH2:18]([O:20][C:21]1[CH:26]=[CH:25][C:24](B(O)O)=[CH:23][CH:22]=1)[CH3:19]>>[OH:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][NH:7][S:8]([C:11]1[CH:16]=[CH:15][C:14]([C:24]2[CH:25]=[CH:26][C:21]([O:20][CH2:18][CH3:19])=[CH:22][CH:23]=2)=[CH:13][CH:12]=1)(=[O:10])=[O:9]

Participants

3

Reactant 2

HCID 27343514-Ethoxyphenylboronic acidHCID 160947214-Bromo-N-(5-hydroxypentyl)benzene-1-sulfonamide

Product 1

HCID 11552300HCID 11552300, compound

Procedure

Using a method analogous to that described in Example 40, 4-bromophenyl-sulfonic acid-(5-hydroxypentyl)-amide and 4-ethoxyphenyl boronic acid were reacted to give the title compound as a white solid. δC (DMSO, 62.9 MHz): 14.7, 22.6, 28.9, 32.0, 42.6, 60.5, 63.2, 115.0, 126.6, 127.1, 128.2, 130.6, 138.4, 143.5 and 158.9.

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-7cb6328edd724754bd96d7d7479339c9
Source dataset
uspto-grants-2011_06
Patent number
US07964643B2

Reaction notes

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