4-Chlorobenzoyl chloride → 4-chloro-N-(2-((4-chlorophenyl)(phenyl)methylamino)-2-oxoethyl)benzamide

HRID 2425185Notes

Reaction equation

HRID 2425185 reaction equation
Cl.[NH2:2][CH2:3][C:4]([NH:6][CH:7]([C:14]1[CH:19]=[CH:18][C:17]([Cl:20])=[CH:16][CH:15]=1)[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)=[O:5].[Cl:21][C:22]1[CH:30]=[CH:29][C:25]([C:26](Cl)=[O:27])=[CH:24][CH:23]=1>>[Cl:21][C:22]1[CH:30]=[CH:29][C:25]([C:26]([NH:2][CH2:3][C:4](=[O:5])[NH:6][CH:7]([C:14]2[CH:19]=[CH:18][C:17]([Cl:20])=[CH:16][CH:15]=2)[C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)=[O:27])=[CH:24][CH:23]=1

Participants

3

Reactant 2

HCID 85014-Chlorobenzoyl chlorideHCID 672464382-Amino-N-[(4-chloro-phenyl)-phenyl-methyl]-acetamide hydrochloride

Product 1

HCID 445936484-chloro-N-(2-((4-chlorophenyl)(phenyl)methylamino)-2-oxoethyl)benzamide

Procedure

Prepared in analogy to example 1.13 from rac-2-amino-N-[(4-chloro-phenyl)-phenyl-methyl]-acetamide hydrochloride (Example 3.1) and 4-chlorobenzoyl chloride.

Sources & evidence

ORD record
ord-5cecfa54bbd642b6932ac4339ae51ad2
Source dataset
uspto-grants-2011_06
Patent number
US07964645B2

Reaction notes

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