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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2425189Generated: October 28, 2026

4-(Trifluoromethyl)benzoic acid → Rac-n-({[(4-chloro-phenyl)-phenyl-methyl]-carbamoyl}-methyl)-4-trifluoromethyl-benzamide

https://huagongshe.com/reaction/2425189

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Trifluoromethyl)benzoic acidHCID 9966—
Reactant2-Amino-N-[(4-chloro-phenyl)-phenyl-methyl]-acetamide hydrochlorideHCID 67246438—
ProductRac-n-({[(4-chloro-phenyl)-phenyl-methyl]-carbamoyl}-methyl)-4-trifluoromethyl-benzamideHCID 59689104—

Reaction Steps

Prepared in analogy to example 1.12 from rac-2-amino-N-[(4-chloro-phenyl)-phenyl-methyl]-acetamide hydrochloride (Example 3.1) and 4-(trifluoromethyl)benzoic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07964645B2
Source datasetuspto-grants-2011_06
ORD IDord-94a8b1e1f01e4455959c2843f156c7a4
Source noteuspto-grants-2011_06