p-(Methylsulphonyl)benzoic acid → HCID 59689174, compound

HRID 2425193Notes

Reaction equation

HRID 2425193 reaction equation
Cl.[NH2:2][CH2:3][C:4]([NH:6][CH:7]([C:14]1[CH:19]=[CH:18][C:17]([Cl:20])=[CH:16][CH:15]=1)[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)=[O:5].[CH3:21][S:22]([C:25]1[CH:33]=[CH:32][C:28]([C:29](O)=[O:30])=[CH:27][CH:26]=1)(=[O:24])=[O:23]>>[Cl:20][C:17]1[CH:18]=[CH:19][C:14]([CH:7]([NH:6][C:4]([CH2:3][NH:2][C:29](=[O:30])[C:28]2[CH:27]=[CH:26][C:25]([S:22]([CH3:21])(=[O:24])=[O:23])=[CH:33][CH:32]=2)=[O:5])[C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)=[CH:15][CH:16]=1

Participants

3

Reactant 2

HCID 77670p-(Methylsulphonyl)benzoic acidHCID 672464382-Amino-N-[(4-chloro-phenyl)-phenyl-methyl]-acetamide hydrochloride

Product 1

HCID 59689174HCID 59689174, compound

Procedure

Prepared in analogy to example 1.12 from rac-2-amino-N-[(4-chloro-phenyl)-phenyl-methyl]-acetamide hydrochloride (Example 3.1) and 4-methylsulphonylbenzoic acid.

Sources & evidence

ORD record
ord-774867a18ff04b209df51126bd1b21b1
Source dataset
uspto-grants-2011_06
Patent number
US07964645B2

Reaction notes

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