Phenylpropionylglycine → HCID 59689115, compound

HRID 2425196Notes

Reaction equation

[C:1]1([CH2:7][CH2:8][C:9]([NH:11][CH2:12][C:13]([OH:15])=O)=[O:10])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.Cl.[C:17]1([CH:23]([NH2:34])[C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][C:25]=2[C:30]([F:33])([F:32])[F:31])[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>>[C:1]1([CH2:7][CH2:8][C:9]([NH:11][CH2:12][C:13](=[O:15])[NH:34][CH:23]([C:17]2[CH:18]=[CH:19][CH:20]=[CH:21][CH:22]=2)[C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][C:25]=2[C:30]([F:31])([F:32])[F:33])=[O:10])[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

Reactant 2

HCID 152323Phenylpropionylglycine

HCID 21528813HCID 21528813, compound

Product 1

HCID 59689115HCID 59689115, compound

Procedure

Prepared in analogy to example 1.1 from mmol (3-phenyl-propionylamino)-acetic acid (CA [56613-60-6]) and rac-C-phenyl-C-(2-trifluoromethyl-phenyl)-methylamine hydrochloride (CA [49703-62-0]).

Sources & evidence

ORD record: ord-e57aef2e0e584da882b10eab794bcba9
Source dataset: uspto-grants-2011_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07964645B2

Reaction notes

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