2-(Trifluoromethyl)benzoic acid → HCID 59689149, compound

HRID 2425215Notes

Reaction equation

HRID 2425215 reaction equation
Cl.[NH2:2][CH2:3][C:4]([NH:6][CH:7]([C:14]1[CH:19]=[CH:18][C:17]([Cl:20])=[CH:16][CH:15]=1)[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)=[O:5].[F:21][C:22]([F:33])([F:32])[C:23]1[CH:31]=[CH:30][CH:29]=[CH:28][C:24]=1[C:25](O)=[O:26]>>[Cl:20][C:17]1[CH:18]=[CH:19][C:14]([CH:7]([NH:6][C:4]([CH2:3][NH:2][C:25](=[O:26])[C:24]2[CH:28]=[CH:29][CH:30]=[CH:31][C:23]=2[C:22]([F:21])([F:32])[F:33])=[O:5])[C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)=[CH:15][CH:16]=1

Participants

3

Reactant 2

HCID 98992-(Trifluoromethyl)benzoic acidHCID 672464382-Amino-N-[(4-chloro-phenyl)-phenyl-methyl]-acetamide hydrochloride

Product 1

HCID 59689149HCID 59689149, compound

Procedure

Prepared in analogy to example 1.12 from rac-2-amino-N-[(4-chloro-phenyl)-phenyl-methyl]-acetamide hydrochloride (Example 3.1) and 2-trifluoromethylbenzoic acid.

Sources & evidence

ORD record
ord-4602d5e2e976468581b3cfa4e32704ec
Source dataset
uspto-grants-2011_06
Patent number
US07964645B2

Reaction notes

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