2,4,5-Trifluorobenzoic acid → HCID 59689123, compound

HRID 2425231Notes

Reaction equation

HRID 2425231 reaction equation
Cl.[NH2:2][CH2:3][C:4]([NH:6][CH:7]([C:14]1[CH:19]=[CH:18][C:17]([Cl:20])=[CH:16][CH:15]=1)[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)=[O:5].[F:21][C:22]1[CH:30]=[C:29]([F:31])[C:28]([F:32])=[CH:27][C:23]=1[C:24](O)=[O:25]>>[Cl:20][C:17]1[CH:18]=[CH:19][C:14]([CH:7]([NH:6][C:4]([CH2:3][NH:2][C:24](=[O:25])[C:23]2[CH:27]=[C:28]([F:32])[C:29]([F:31])=[CH:30][C:22]=2[F:21])=[O:5])[C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)=[CH:15][CH:16]=1

Participants

3

Reactant 2

HCID 5211702,4,5-Trifluorobenzoic acidHCID 672464382-Amino-N-[(4-chloro-phenyl)-phenyl-methyl]-acetamide hydrochloride

Product 1

HCID 59689123HCID 59689123, compound

Procedure

Prepared in analogy to example 1.12 from rac-2-amino-N-[(4-chloro-phenyl)-phenyl-methyl]-acetamide hydrochloride (Example 3.1) and 2,4,5-trifluorobenzoic acid.

Sources & evidence

ORD record
ord-4bab6ff1310d41ccb97d55b8f076dc6c
Source dataset
uspto-grants-2011_06
Patent number
US07964645B2

Reaction notes

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