2-Chloro-4-fluorobenzoic acid → HCID 59689150, compound

HRID 2425234Notes

Reaction equation

HRID 2425234 reaction equation
Cl.[NH2:2][CH2:3][C:4]([NH:6][CH:7]([C:14]1[CH:19]=[CH:18][C:17]([Cl:20])=[CH:16][CH:15]=1)[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)=[O:5].[Cl:21][C:22]1[CH:30]=[C:29]([F:31])[CH:28]=[CH:27][C:23]=1[C:24](O)=[O:25]>>[Cl:21][C:22]1[CH:30]=[C:29]([F:31])[CH:28]=[CH:27][C:23]=1[C:24]([NH:2][CH2:3][C:4](=[O:5])[NH:6][CH:7]([C:14]1[CH:19]=[CH:18][C:17]([Cl:20])=[CH:16][CH:15]=1)[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)=[O:25]

Participants

3

Reactant 2

HCID 752592-Chloro-4-fluorobenzoic acidHCID 672464382-Amino-N-[(4-chloro-phenyl)-phenyl-methyl]-acetamide hydrochloride

Product 1

HCID 59689150HCID 59689150, compound

Procedure

Prepared in analogy to example 1.12 from rac-2-amino-N-[(4-chloro-phenyl)-phenyl-methyl]-acetamide hydrochloride (Example 3.1) and 2-chloro-4-fluorobenzoic acid.

Sources & evidence

ORD record
ord-0e79a84f174241d4965a393b0c5fc26f
Source dataset
uspto-grants-2011_06
Patent number
US07964645B2

Reaction notes

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