4-Fluorohippuric acid → HCID 24900238, compound

HRID 2425241Notes

Reaction equation

HRID 2425241 reaction equation
[F:1][C:2]1[CH:14]=[CH:13][C:5]([C:6](=[O:12])[NH:7][CH2:8][C:9]([OH:11])=O)=[CH:4][CH:3]=1.[F:15][C:16]1[CH:17]=[C:18]([CH:23]([NH2:30])[C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)[CH:19]=[C:20]([F:22])[CH:21]=1>>[F:15][C:16]1[CH:17]=[C:18]([CH:23]([NH:30][C:9]([CH2:8][NH:7][C:6](=[O:12])[C:5]2[CH:4]=[CH:3][C:2]([F:1])=[CH:14][CH:13]=2)=[O:11])[C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)[CH:19]=[C:20]([F:22])[CH:21]=1

Participants

3

Reactant 2

HCID 6993414-Fluorohippuric acidHCID 24689252HCID 24689252, compound

Product 1

HCID 24900238HCID 24900238, compound

Procedure

Prepared in analogy to example 1.1 from 4-fluoro-hippuric acid (CA [366-79-0]) and rac-C-(3,5-difluoro-phenyl)-C-phenyl-methylamine (example 4.3).

Sources & evidence

ORD record
ord-d7b2116611924daaa5dd13cdd0b12ce6
Source dataset
uspto-grants-2011_06
Patent number
US07964645B2

Reaction notes

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