4-Fluorohippuric acid → HCID 59689127, compound

HRID 2425242Notes

Reaction equation

HRID 2425242 reaction equation
[F:1][C:2]1[CH:14]=[CH:13][C:5]([C:6](=[O:12])[NH:7][CH2:8][C:9]([OH:11])=O)=[CH:4][CH:3]=1.[Cl:15][C:16]1[CH:21]=[CH:20][C:19]([N+:22]([O-:24])=[O:23])=[CH:18][C:17]=1[CH:25]([NH2:32])[C:26]1[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=1>>[Cl:15][C:16]1[CH:21]=[CH:20][C:19]([N+:22]([O-:24])=[O:23])=[CH:18][C:17]=1[CH:25]([NH:32][C:9]([CH2:8][NH:7][C:6](=[O:12])[C:5]1[CH:4]=[CH:3][C:2]([F:1])=[CH:14][CH:13]=1)=[O:11])[C:26]1[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=1

Participants

3

Reactant 2

HCID 6993414-Fluorohippuric acidHCID 59689108HCID 59689108, compound

Product 1

HCID 59689127HCID 59689127, compound

Procedure

Prepared in analogy to example 1.1 from 4-fluoro-hippuric acid (CA [366-79-0]) and rac-C-(2-chloro-5-nitro-phenyl)-C-phenyl-methylamine (example 4.4).

Sources & evidence

ORD record
ord-fd2fefb982c74acd816a6ee66fe62651
Source dataset
uspto-grants-2011_06
Patent number
US07964645B2

Reaction notes

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