4-Fluorohippuric acid → HCID 24896772, compound

HRID 2425246Notes

Reaction equation

HRID 2425246 reaction equation
[F:1][C:2]1[CH:14]=[CH:13][C:5]([C:6](=[O:12])[NH:7][CH2:8][C:9]([OH:11])=O)=[CH:4][CH:3]=1.[F:15][C:16]1[CH:21]=[CH:20][C:19]([CH:22]([NH2:33])[C:23]2[CH:28]=[CH:27][CH:26]=[C:25]([C:29]([F:32])([F:31])[F:30])[CH:24]=2)=[CH:18][CH:17]=1>>[F:1][C:2]1[CH:3]=[CH:4][C:5]([C:6]([NH:7][CH2:8][C:9](=[O:11])[NH:33][CH:22]([C:19]2[CH:18]=[CH:17][C:16]([F:15])=[CH:21][CH:20]=2)[C:23]2[CH:28]=[CH:27][CH:26]=[C:25]([C:29]([F:30])([F:31])[F:32])[CH:24]=2)=[O:12])=[CH:13][CH:14]=1

Participants

3

Reactant 2

HCID 6993414-Fluorohippuric acidHCID 24688967HCID 24688967, compound

Product 1

HCID 24896772HCID 24896772, compound

Procedure

Prepared in analogy to example 1.1 from 4-fluoro-hippuric acid (CA [366-79-0]) and rac-C-(4-fluoro-phenyl)-C-(3-trifluoromethyl-phenyl)-methylamine (example 4.5).

Sources & evidence

ORD record
ord-f9970a78adf84e3a98c561fdd249838b
Source dataset
uspto-grants-2011_06
Patent number
US07964645B2

Reaction notes

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