4-Fluorohippuric acid → HCID 24896774, compound

HRID 2425247Notes

Reaction equation

HRID 2425247 reaction equation
[F:1][C:2]1[CH:14]=[CH:13][C:5]([C:6](=[O:12])[NH:7][CH2:8][C:9]([OH:11])=O)=[CH:4][CH:3]=1.[C:15]1([CH3:33])[CH:20]=[CH:19][C:18]([CH:21]([NH2:32])[C:22]2[CH:27]=[CH:26][CH:25]=[C:24]([C:28]([F:31])([F:30])[F:29])[CH:23]=2)=[CH:17][CH:16]=1>>[F:1][C:2]1[CH:3]=[CH:4][C:5]([C:6]([NH:7][CH2:8][C:9](=[O:11])[NH:32][CH:21]([C:18]2[CH:17]=[CH:16][C:15]([CH3:33])=[CH:20][CH:19]=2)[C:22]2[CH:27]=[CH:26][CH:25]=[C:24]([C:28]([F:29])([F:30])[F:31])[CH:23]=2)=[O:12])=[CH:13][CH:14]=1

Participants

3

Reactant 2

HCID 6993414-Fluorohippuric acidHCID 43197727HCID 43197727, compound

Product 1

HCID 24896774HCID 24896774, compound

Procedure

Prepared in analogy to example 1.1 from 4-fluoro-hippuric acid (CA [366-79-0]) and rac-C-p-tolyl-C-(3-trifluoromethyl-phenyl)-methylamine (example 4.6).

Sources & evidence

ORD record
ord-49aeb069316d4108a2fcd8ed9d179180
Source dataset
uspto-grants-2011_06
Patent number
US07964645B2

Reaction notes

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