4-Fluorohippuric acid → HCID 59689180, compound

HRID 2425249Notes

Reaction equation

HRID 2425249 reaction equation
[F:1][C:2]1[CH:14]=[CH:13][C:5]([C:6](=[O:12])[NH:7][CH2:8][C:9]([OH:11])=O)=[CH:4][CH:3]=1.[F:15][C:16]([F:37])([F:36])[O:17][C:18]1[CH:23]=[CH:22][C:21]([CH:24]([NH2:35])[C:25]2[CH:30]=[CH:29][CH:28]=[C:27]([C:31]([F:34])([F:33])[F:32])[CH:26]=2)=[CH:20][CH:19]=1>>[F:1][C:2]1[CH:3]=[CH:4][C:5]([C:6]([NH:7][CH2:8][C:9](=[O:11])[NH:35][CH:24]([C:21]2[CH:22]=[CH:23][C:18]([O:17][C:16]([F:15])([F:36])[F:37])=[CH:19][CH:20]=2)[C:25]2[CH:30]=[CH:29][CH:28]=[C:27]([C:31]([F:33])([F:34])[F:32])[CH:26]=2)=[O:12])=[CH:13][CH:14]=1

Participants

3

Reactant 2

HCID 6993414-Fluorohippuric acidHCID 59689117HCID 59689117, compound

Product 1

HCID 59689180HCID 59689180, compound

Procedure

Prepared in analogy to example 1.1 from 4-fluoro-hippuric acid (CA [366-79-0]) and rac-C-(4-trifluoromethoxy-phenyl)-C-(3-trifluoromethyl-phenyl)-methylamine (example 4.8).

Sources & evidence

ORD record
ord-b91cecbb22e24ba09bcacb345deb710a
Source dataset
uspto-grants-2011_06
Patent number
US07964645B2

Reaction notes

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