4-Fluorohippuric acid → HCID 59689119, compound

HRID 2425252Notes

Reaction equation

HRID 2425252 reaction equation
[F:1][C:2]1[CH:14]=[CH:13][C:5]([C:6](=[O:12])[NH:7][CH2:8][C:9]([OH:11])=O)=[CH:4][CH:3]=1.Cl.[S:16]1[C:20]([CH:21]([NH2:28])[C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)=[CH:19][CH:18]=[N:17]1>>[F:1][C:2]1[CH:3]=[CH:4][C:5]([C:6]([NH:7][CH2:8][C:9](=[O:11])[NH:28][CH:21]([C:20]2[S:16][N:17]=[CH:18][CH:19]=2)[C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)=[O:12])=[CH:13][CH:14]=1

Participants

3

Reactant 2

HCID 6993414-Fluorohippuric acidHCID 67246492HCID 67246492, compound

Product 1

HCID 59689119HCID 59689119, compound

Procedure

Prepared in analogy to example 1.1 from 4-fluoro-hippuric acid (CA [366-79-0]) and rac-C-isothiazol-5-yl-C-phenyl-methylamine hydrochloride (example 4.9).

Sources & evidence

ORD record
ord-0246197ff97f42268ebb5fff33c7d7a1
Source dataset
uspto-grants-2011_06
Patent number
US07964645B2

Reaction notes

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