4-Fluorohippuric acid → HCID 24896773, compound

HRID 2425254Notes

Reaction equation

HRID 2425254 reaction equation
[F:1][C:2]1[CH:14]=[CH:13][C:5]([C:6](=[O:12])[NH:7][CH2:8][C:9]([OH:11])=O)=[CH:4][CH:3]=1.Cl.[F:16][C:17]1[CH:18]=[C:19]([CH:23]([NH2:34])[C:24]2[CH:29]=[CH:28][CH:27]=[C:26]([C:30]([F:33])([F:32])[F:31])[CH:25]=2)[CH:20]=[CH:21][CH:22]=1>>[F:1][C:2]1[CH:3]=[CH:4][C:5]([C:6]([NH:7][CH2:8][C:9](=[O:11])[NH:34][CH:23]([C:19]2[CH:20]=[CH:21][CH:22]=[C:17]([F:16])[CH:18]=2)[C:24]2[CH:29]=[CH:28][CH:27]=[C:26]([C:30]([F:31])([F:32])[F:33])[CH:25]=2)=[O:12])=[CH:13][CH:14]=1

Participants

3

Reactant 2

HCID 6993414-Fluorohippuric acidHCID 67246222HCID 67246222, compound

Product 1

HCID 24896773HCID 24896773, compound

Procedure

Prepared in analogy to example 1.1 from 4-fluoro-hippuric acid (CA [366-79-0]) and rac-C-(3-fluoro-phenyl)-C-(3-trifluoromethyl-phenyl)-methylamine hydrochloride (example 4.10).

Sources & evidence

ORD record
ord-f6da7fa793504cddaf41d391989b12c6
Source dataset
uspto-grants-2011_06
Patent number
US07964645B2

Reaction notes

Loading…