2-Chloro-3-(trifluoromethyl)benzoic acid → HCID 59689182, compound

HRID 2425259Notes

Reaction equation

HRID 2425259 reaction equation
[NH2:1][CH2:2][C:3]([NH:5][CH:6]([C:14]1[CH:19]=[CH:18][CH:17]=[C:16]([F:20])[CH:15]=1)[C:7]1[CH:12]=[CH:11][CH:10]=[C:9]([F:13])[CH:8]=1)=[O:4].[Cl:21][C:22]1[C:30]([C:31]([F:34])([F:33])[F:32])=[CH:29][CH:28]=[CH:27][C:23]=1[C:24](O)=[O:25]>>[F:20][C:16]1[CH:15]=[C:14]([CH:6]([NH:5][C:3]([CH2:2][NH:1][C:24](=[O:25])[C:23]2[CH:27]=[CH:28][CH:29]=[C:30]([C:31]([F:32])([F:33])[F:34])[C:22]=2[Cl:21])=[O:4])[C:7]2[CH:12]=[CH:11][CH:10]=[C:9]([F:13])[CH:8]=2)[CH:19]=[CH:18][CH:17]=1

Participants

3

Reactant 2

HCID 27366772-Chloro-3-(trifluoromethyl)benzoic acidHCID 596891532-amino-N-[bis-(3-fluoro-phenyl)-methyl]-acetamide

Product 1

HCID 59689182HCID 59689182, compound

Procedure

Prepared in analogy to example 1.12 from 2-amino-N-[bis-(3-fluoro-phenyl)-methyl]-acetamide (example 3.4) and 2-chloro-3-trifluoromethyl-benzoic acid.

Sources & evidence

ORD record
ord-5987ced064634645be2c52f8143552e9
Source dataset
uspto-grants-2011_06
Patent number
US07964645B2

Reaction notes

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