HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(4-Chlorophenyl)-1-[3-(5,11-dihydro-7-hydroxy [1]benzoxepino [2,3-b]pyridin-5-ylidene)propyl]piperidin-4-ol → 5-Chloro-1'-[3-(5,11-dihydro-7-(2-methoxyethyl)oxy[1]benzoxepino[2,3-b]pyridin-5-ylidene)propyl]spiro[isobenzofuran-1 (3H), 4'-piperidine]
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(4-Chlorophenyl)-1-[3-(5,11-dihydro-7-hydroxy [1]benzoxepino [2,3-b]pyridin-5-ylidene)propyl]piperidin-4-ol | HCID 66757538 | — |
| Reactant | 5-Chloro-1'-[3-(5,11-dihydro-7-hydroxy[1]benzoxepino [2,3-b]pyridin-5-ylidene)propyl]spiro[isobenzofuran-1(3H),4'-piperidine] | HCID 66973919 | — |
| Product | 5-Chloro-1'-[3-(5,11-dihydro-7-(2-methoxyethyl)oxy[1]benzoxepino[2,3-b]pyridin-5-ylidene)propyl]spiro[isobenzofuran-1 (3H), 4'-piperidine] | HCID 66973784 | — |
Reaction Steps
The titled compound was prepared by following the procedure of example 175, but replacing the product of example 44 with the product of example 196.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08653096B2 |
| Source dataset | uspto-grants-2014_02 |
| ORD ID | ord-671d4e947cb9413d90123ff7cdee9003 |
| Source note | uspto-grants-2014_02 |