4-(1,1-Dimethyl-2-propynyloxy)anisole → 6-Methoxy-2,2-dimethyl-2H-1-benzopyran

Participants

Reaction Steps

A solution of 4-(1,1-dimethyl-2-propynyloxy)anisole in 1,2-dichlorobenzene (50 mL) was stirred at 190° C. for 2 hours. Upon the completion of the reaction, the solvent was distilled off under a reduced pressure. The residue was purified by column chromatography (hexane/chloroform=3/1) and the aimed product was obtained as red oily substance (2-step, yield: 61%).

Provenance & Evidence