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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2425391Generated: October 26, 2026

tert-butyl N-[(3S)-piperidin-3-yl]carbamate → Hydrochloric Acid

https://huagongshe.com/reaction/2425391

Reaction equation

Participants

RoleNameHCIDCharge
Reactanttert-butyl N-[(3S)-piperidin-3-yl]carbamateHCID 1514171—
Reactant3-(Boc-amino)piperidineHCID 4233041—
Reactant3-(Tert-butoxycarbonylamino)-1-(4-chloro-5-isoquinolinesulfonyl)piperidineHCID 67242669—
ProductHydrochloric AcidHCID 313—
Product(r/s)-3-Amino-1-(4-chloro-5-isoquinolinesulfonyl)piperidineHCID 67242690—

Reaction Steps

3-(tert-Butoxycarbonylamino)-1-(4-chloro-5-isoquinolinesulfonyl)piperidine (Intermediate 18) can be prepared by using 3-(tert-butoxycarbonylamino)piperidine in the method of Example 21-1, Step A instead of (S)-3-(tert-butoxycarbonylamino)piperidine, and then used in the method of Step B in a similar manner to obtain the title compound as hydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07964613B2
Source datasetuspto-grants-2011_06
ORD IDord-41910abbcd89441891856960d613f831
Source noteuspto-grants-2011_06