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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2425427Generated: November 2, 2026

(S)-3-(tert-butoxycarbonyl)amino-1-(1,4-dichloro-5-isoquinolinesulfonyl)pyrrolidine → Hydrochloric Acid

https://huagongshe.com/reaction/2425427

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(S)-3-(tert-butoxycarbonyl)amino-1-(1,4-dichloro-5-isoquinolinesulfonyl)pyrrolidineHCID 86627808—
Reactant3-[n-(Tert-butoxycarbonyl)-n-methylamino]-1-(1-chloro-4-bromo-5-isoquinolinesulfonyl)pyrrolidineHCID 87322379—
ProductHydrochloric AcidHCID 313—
Product(r/s)-1-(1-Amino-4-bromo-5-isoquinolinesulfonyl)-3-(methylamino)pyrrolidineHCID 67242682—

Reaction Steps

Intermediate 24 can be used in the method of Example 39-1 instead of Intermediate 26a to obtain the title compound as hydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07964613B2
Source datasetuspto-grants-2011_06
ORD IDord-b57963f564b14f5bb149afb8064de568
Source noteuspto-grants-2011_06