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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2425429Generated: October 28, 2026

(R)-3-[N-(tert-Butoxycarbonyl)-N-methylamino]-1-(1-chloro-4-bromo-5-isoquinolinesulfonyl)pyrrolidine → Hydrochloric Acid

https://huagongshe.com/reaction/2425429

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(R)-3-[N-(tert-Butoxycarbonyl)-N-methylamino]-1-(1-chloro-4-bromo-5-isoquinolinesulfonyl)pyrrolidineHCID 86627806—
Reactant(S)-3-(tert-butoxycarbonyl)amino-1-(1,4-dichloro-5-isoquinolinesulfonyl)pyrrolidineHCID 86627808—
ProductHydrochloric AcidHCID 313—
ProductHCID 67242679HCID 67242679—

Reaction Steps

Intermediate 24b can be used in the method of Example 39-1 instead of Intermediate 26a to obtain the title compound as hydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07964613B2
Source datasetuspto-grants-2011_06
ORD IDord-e59c7296801443c9ad6708bac0ba42ac
Source noteuspto-grants-2011_06