Piperazin-2-one → HCID 11685782, compound

Participants

Reaction Steps

4-[(4S,5R)-2-(4-tert-Butyl-2-ethoxy-phenyl)-4,5-bis-(4-fluoro-phenyl)-4,5-dihydro-imidazole-1-carbonyl]-piperazin-2-one hydrochloride was prepared from (4S,5R)-2-(4-tert-butyl-2-ethoxy-phenyl)-4,5-bis-(4-fluoro-phenyl)-4,5-dihydro-imidazole-1-carbonyl chloride (example 12a) and 2-piperazinone (Avocado Organics) in an analogous manner as described in example 25. LR-MS: 561.4 [(M+H)+]

Provenance & Evidence