HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 20802879, compound → HCID 11592795, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 20802879 | HCID 20802879 | — |
| Reactant | (4S,5R)-2-(4-tert-butyl-2-ethoxy-phenyl)-4,5-bis-(4-chloro-phenyl)-4,5-dihydro-imidazole-1-carbonyl chloride | HCID 57732375 | — |
| Product | HCID 11592795 | HCID 11592795 | — |
Reaction Steps
4-{4-[(4S,5R)-2-(4-tert-Butyl-2-ethoxy-phenyl)-4,5-bis-(4-chloro-phenyl)-4,5-dihydro-imidazole-1-carbonyl]-piperazin-1-yl}-butan-2-one hydrochloride was prepared from (4S,5R)-2-(4-tert-butyl-2-ethoxy-phenyl)-4,5-bis-(4-chloro-phenyl)-4,5-dihydro-imidazole-1-carbonyl chloride (example 11) and 4-piperazin-1-yl-butan-2-one (example 18c) in an analogous manner as described in example 25. LR-MS: 649.4 [(M+H)+]
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07964724B2 |
| Source dataset | uspto-grants-2011_06 |
| ORD ID | ord-fb1a5598708447b9baa0a1e195877f47 |
| Source note | uspto-grants-2011_06 |