4-(1-Pyrrolidinyl)piperidine → HCID 11549303, compound

Participants

Role	Name	HCID	Charge
Reactant	4-(1-Pyrrolidinyl)piperidine	HCID 78703	—
Reactant	(4S,5R)-2-(4-tert-butyl-2-ethoxy-phenyl)-4,5-bis-(4-chloro-phenyl)-4,5-dihydro-imidazole-1-carbonyl chloride	HCID 57732375	—
Product	HCID 11549303	HCID 11549303	—

Reaction Steps

[(4S,5R)-2-(4-tert-Butyl-2-ethoxy-phenyl)-4,5-bis-(4-chloro-phenyl)-4,5-dihydro-imidazol-1-yl]-(4-pyrrolidin-1-yl-piperidin-1-yl)-methanone hydrochloride was prepared from (4S,5R)-2-(4-tert-butyl-2-ethoxy-phenyl)-4,5-bis-(4-chloro-phenyl)-4,5-dihydro-imidazole-1-carbonyl chloride (example 11) and 4-pyrrolidin-1-yl-piperidine in an analogous manner as described in example 25. LR-MS: 647.4 [(M+H)+]

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07964724B2
Source dataset	uspto-grants-2011_06
ORD ID	ord-149c04944e194d95ba2b1348594c743d
Source note	uspto-grants-2011_06